Friday, November 7, 2014
The second and last day of this CRG Symposium was focused on Cell Reprogramming, Aging and Cancer. Many results were shown on the link between Senescence and Cancer….
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Friday, November 7, 2014
The epidermis is a multi-layered structure in which epigenetic factors are differentially expressed. The investigation of this dynamic expression using an in vitro differentiation system reveals a strong…
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Friday, November 7, 2014
Despite the high interest in the reprogramming field due to the potential therapeutical applications, the possibility to change the cellular identity in vivo within the tissues will represent…
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Friday, November 7, 2014
Marius Wernig is the scientist who first directly converted fibroblast into Induced Neurons (iN) with the ectopic expression of only three factors. In this talk, he argumented that…
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Friday, November 7, 2014
During senescence, cells undergo a proliferative arrest that seems to induce a tumorigenic effect on the neighbouring cells through secretion of specific molecules. The identification of senescence-related genes…
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Friday, November 7, 2014
Austin Smith is probably the investigator that is constantly giving more indications on how to capture the ground state of pluripotent stem cells. His work is based on…
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Friday, November 7, 2014
The path of cancer evolution dictates the tumor response to therapy and creates unique vulnerabilities that represent therapeutic opportunities. Based on this concept, Lowe’s Lab is developing powerful…
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Friday, November 7, 2014
The formation of digits during development is a high regulated process coordinates by the Hoxd genes. By analyzing the chromosome conformation and Hox transcriptional regulation during the process,…
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Friday, November 7, 2014
The liver is an organ with a high regeneration potential and Markus Grompe is one of the most excellent scientists working in this field. Using lineage tracing mice,…
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Friday, November 7, 2014
The concept that it is possible to reprogram the cell fate for therapeutic purpose is one of the hottest field of the last years. Kenneth Zaret is investigating…
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